amyotrophic lateral sclerosis

noun

amyo·​tro·​phic lateral sclerosis ˌā-ˌmī-ə-ˈtrō-fik- How to pronounce amyotrophic lateral sclerosis (audio) -ˈträ- How to pronounce amyotrophic lateral sclerosis (audio)
: a rare progressive degenerative fatal disease affecting the motor neurons, usually beginning in middle age, and characterized especially by increasing and spreading muscular weakness and atrophy
abbreviation ALS

called also Lou Gehrig's disease

Examples of amyotrophic lateral sclerosis in a Sentence

Recent Examples on the Web
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The program funds research into amyotrophic lateral sclerosis (ALS), traumatic brain injuries (TBI), and epilepsy. Emily Kay Votruba, EverydayHealth.com, 11 Apr. 2025 On April 10, Dane announced that he had been diagnosed with amyotrophic lateral sclerosis (ALS). Jordana Comiter, People.com, 11 Apr. 2025 Eric Dane has been diagnosed with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. J. Kim Murphy, Variety, 11 Apr. 2025 Euphoria star Eric Dane has amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's Disease. Lauren Huff, EW.com, 11 Apr. 2025 See All Example Sentences for amyotrophic lateral sclerosis

Word History

Etymology

a- entry 2 + my- + -trophic

First Known Use

1875, in the meaning defined above

Time Traveler
The first known use of amyotrophic lateral sclerosis was in 1875

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Cite this Entry

“Amyotrophic lateral sclerosis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/amyotrophic%20lateral%20sclerosis. Accessed 24 Apr. 2025.

Medical Definition

amyotrophic lateral sclerosis

noun
: a rare fatal progressive degenerative disease that affects pyramidal motor neurons, usually begins in middle age, and is characterized especially by increasing and spreading muscular weakness
abbreviation ALS

called also Lou Gehrig's disease

More from Merriam-Webster on amyotrophic lateral sclerosis

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